This was my little guide book of Prague where I wrote down almost every place I went during my exchange time at Umprum. Mostly it contains bars, galleries, museums and music venues.
The area around Náměstí Jana Palacha. The student pub, Hany Bany at Veleslavínova is a smokey joint, with Pulp Fiction posters and cheap quick food. Umprum is the Academy of Art, Architecture and Design where I went to school. If you happen to be in Prague for their semestral exhibition, it is really worth visiting. The Rudolfinum functions as a great art gallery as well as concert hall and is the home of the Czech Philharmonic Orchestra. U(P)M is the museum of decorative arts and lastly there is the kaffe+berliner, which is a small supermarket, Žabka where you can get a coffee and a doughnut for 1€.
There are always a couple of nice Balkan bands playing here.
At the Meet Factoryyou can see theater, exhibitions or concerts. It is located on a dodgy place by the tracks at Smíchov station but it is worth a trip if something good is happening.
Palác Akropolis is always worth checking out for concerts, or if you are in the Žižkov area late at night (it is the old working class district of Prague with a lot of nice pubs) then drop by to dance in one of the three small underground clubs.
U Sudu is a pub with 3 1/2 levels under ground, with three bars, that each have their own atmosphere and a baby foot room, they always have a spcial offer on Mojitos and serve a great Burčák in August right in the beginning of the wineharvest. It is located right by the tram stops at Lazarská and a few minutes away from the sausage/burger stands by Václavské náměstí, they are open all night if you could go for at midnight snack.
At Bukowski there are beers for 7 kc at sundays and free Sangria for females at sundays. I don’t think this is an all night offer, they hav a certain amount and then it all depends on how many people show up.
Restaurace u veverky is a nice Czech restaurant at Hradčanská, there is also Restaurace Dejvická Sokolovna right by the station where I had the dragons eye once, it was one red and one green chilli wrapped in ham, wrapped in cheese, wrapped in thinned cutlet and it was all coated with bread crumbs and cornflakes to imitate the dragons skin. It was the best experience with mashed potatos and a nice cold beer, but if you eat here, mak sure you are hungry or split a main course and a salad.
You can get almost anywhere in the centre of Prague with the metro, but remember that it stops running at twelve on weekdays and one at weekends. And it is in the underground that you will meet the most ticket inspectors.